Admit rate has ranged 30%–64% over the last 5 years — notably volatile. Source: IPEDS via Urban Institute.
Acceptance & SAT from Common Data Set / IPEDS; net price, earnings & graduation from the U.S. Dept. of Education College Scorecard. Figures lag ~1–2 years — verify with the school.
Mayo Clinic College of Medicine and Science is a hyper-specialized powerhouse for health sciences, where students train alongside world-renowned clinicians and researchers at one of the most prestigious medical institutions on the planet. With acceptance rates as low as 1.8% for its MD program and a staggering 93% graduation rate, it attracts elite students who thrive in its intensely collaborative, hands-on environment. The college’s 450+ programs—from phlebotomy to biomedical research—offer unparalleled clinical immersion, with outcomes like 100% PANCE pass rates for physician assistant graduates and nearly half of family medicine alumni practicing in rural Minnesota.
Admission requirements
Test-blind — scores not considered
Required
Letters of recommendation
College-prep program
Considered (not required)
Grade point average
Source: IPEDS Admissions survey (2022) via Urban Institute. Covers formal factors only — it does not reflect essays, extracurriculars, or other holistic criteria.
More details
Undergrad enrollment
309
In-state tuition
$3,257
Out-of-state tuition
$3,257
Graduation Rate
93%
Programs Offered
450+
Student-Faculty Ratio
11:1
Financial Aid Recipients
100% of undergraduates
PA Program PANCE Pass Rate
100%
Acceptance Rate (MD Program)
3.4%
Acceptance Rate (Undergraduate)
39%
Outcomes & value
Outcomes & value
Median earnings (10 yr)
$79,652
Median debt at graduation
$10,500
Pell (lower-income) share
16%
Endowment / student
$3,389,599
Earnings = median of students working ~10 years after entry; debt = median of graduates. Value divides 10-yr earnings by one year’s net price — read it as earnings per dollar of annual cost, not a full lifetime ROI; it favors lower-cost schools. Source: U.S. Dept. of Education College Scorecard. Figures lag ~2 years and reflect all students, not your intended major.
Financial health
3.0 / 3.0Meets the federal financial-responsibility standard
U.S. Dept. of Education Financial Responsibility Composite Score (FY2022-23). Scale −1.0 to 3.0; ≥1.5 meets the standard. Reported for private nonprofit & for-profit institutions only — public universities are state-backed and not scored, so this is a stability signal, not a ranking.
Top-earning majors
Median earnings by field of study (highest credential), ~2 years after completion.
Clinical/Medical Laboratory Science/Research and Allied Professions$62,463
Source: U.S. Dept. of Education College Scorecard (field-of-study earnings). Figures cover graduates who received federal aid and lag ~2 years; not all programs report data.
Campus & location
Campus safety
On-campus violent crimes (2024)
51
Per 1,000 students
165.05
On-campus criminal offenses classed as violent (murder/non-negligent manslaughter, rape, robbery, aggravated assault) for the most recent reported year. Source: U.S. Dept. of Education Campus Safety and Security (Clery Act). Counts reflect what’s reported to the school, and urban campuses often report more partly due to non-student incidents nearby — read alongside campus size and setting, not as a standalone safety verdict.
Climate
Pleasant days / yr
93
Summer high
80°F
Winter low
11°F
Annual rain
37.8"
Annual snow
41.6"
Natural-hazard risk
Relatively Moderate
Pleasant days counts days per year with a mean temperature of 55–75°F, a high at or below 90°F, a low at or above 45°F, and little precipitation — a transparent comfort measure, not a weighting we invented. Computed from Open-Meteo ERA5 daily history (2019–2023). Natural-hazard risk is the county’s composite rating from the FEMA National Risk Index.
Quick answers
What is the acceptance rate at Mayo Clinic College of Medicine and Science?
Mayo Clinic College of Medicine and Science's acceptance rate is approximately 39% (Rochester, MN), based on the most recent figures we compiled from public and primary sources.
How many undergraduates attend Mayo Clinic College of Medicine and Science?
Mayo Clinic College of Medicine and Science enrolls approximately 309 undergraduate students.
Where is Mayo Clinic College of Medicine and Science located?
Mayo Clinic College of Medicine and Science is located in Rochester, MN.
Admissions
Gaining admission to Mayo Clinic College of Medicine and Science is a feat reserved for the most exceptional applicants, particularly in its flagship MD program. The Mayo Clinic Alix School of Medicine reported a 3.4% acceptance rate for its 2025 class, selecting just 204 students from 5,921 applications. Other sources cite even more competitive figures, with some reporting rates as low as 1.84%. Undergraduate programs are slightly more accessible but still selective, with a 39% acceptance rate (55 admits from 141 applications) in 2024. The college doesn’t publicly disclose average GPA or test scores, but its emphasis on Holistic admissionsA review that weighs the whole applicant — grades, essays, activities, and context — rather than relying on test scores and GPA alone. suggests academic excellence alone isn’t enough—applicants must demonstrate alignment with Mayo’s collaborative ethos and clinical passion.
MD program selectivity: 3.4% Acceptance rateThe share of applicants a college admits in a given year. A 10% acceptance rate means it admits about 1 in 10 applicants. (2025), 5,921 applications for 204 spots
Undergraduate selectivity: 39% acceptance rate (2024), though some programs (e.g., biomedical research) may be more competitive
Student satisfaction: 97% of medical students rate health services positively (vs. 81% national average), with 100% satisfaction in career preparation support
Mayo Clinic’s academic offerings are a gold standard in health sciences, with 450+ programs spanning clinical practice, surgery, and biomedical research. The Mayo Clinic School of Health Sciences alone provides 140+ allied health programs, including top-ranked tracks in phlebotomy (104 graduates), radiologic technology (45), and ultrasound sonography (32). What sets Mayo apart is its fully integrated clinical training—students learn within the Mayo Clinic system, working alongside practicing physicians and researchers. The graduate school of biomedical sciences boasts 29.8% of its publications in the top 5% of cited journals, reflecting its research rigor. Programs emphasize interdisciplinary collaboration; as one PhD student noted, the culture rejects 'siloed science' in favor of team-driven breakthroughs.
Life at Mayo Clinic College revolves around deep immersion in medicine—think less frat parties, more snow trips organized by the Student Life & Wellness Committee (SLWC). The 11:1 student-faculty ratio ensures close mentorship, while wellness resources prioritize balancing the intense workload. Students describe a ‘collaborative culture’ (a recurring theme in Instagram testimonials) where peer support is as vital as academic rigor. Housing and traditional campus amenities take a backseat to clinical rotations, but the college fosters community through events like Arizona campus snow outings and research symposiums. Notably, 97% of students report satisfaction with health services—unsurprising given they’re literally at Mayo Clinic.
Mayo’s outcomes read like a medical aspirational fantasy:
100% PANCE pass rates for physician assistant graduates (2022-2023)
100% job placement for those same PA cohorts
93% graduation rate (far above the 68% certificate-program benchmark)
46% of family medicine alumni practice in Minnesota, with 43-48% in rural areas
Early-career salaries average $60,000, though this likely skews higher for MDs and surgical specialists. The college’s proximity to Mayo Clinic’s hiring pipeline gives graduates an edge, with many transitioning directly into residencies or staff roles within the system.
Tuition details are not publicly disclosed for most programs, but the MD program offers need-based scholarships, grants, and loans. Notably, 100% of full-time undergraduates receive aid, though the average award is modest at $2,018—far below the $10,457 national average for comparable institutions. This suggests Mayo’s aid leans heavily on loans rather than grants. The Net priceWhat a family actually pays after grants and scholarships are subtracted from the sticker price — usually far less than the published cost. calculator hints at significant variability, with some students likely paying full freight while others secure institutional support. Pro tip: Reach out to mayofinaid@mayo.edu for program-specific cost breakdowns.
Mayo Clinic College isn’t just a school—it’s a direct pipeline to the most respected name in American medicine. Where else can phlebotomy students train in the same labs as Nobel laureates, or MD candidates scrub into surgeries during their first year? The integration with Mayo Clinic’s hospitals and research centers creates a learning environment that’s more residency than classroom. Its 3.4% MD acceptance rate rivals Ivy League undergrad programs, while outcomes like 100% PA certification pass rates validate its pedagogical rigor. For students who want to skip the theoretical and dive into hands-on patient care and breakthrough research, there’s simply no comparable option.
Mayo Clinic College of Medicine and Science logo · sourceCampus and Community - Mayo Clinic College of Medicine & Science · sourceCampus and Community - Mayo Clinic College of Medicine & Science · sourceRochester, Minnesota - Campus and Community - Mayo Clinic College of Medicine & Science · source
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